Nicotine is a naturally produced alkaloid in the nightshade family of plants and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits where it acts as a receptor antagonist.

निकोटीन एक रासायनिक यौगिक है। यह एक शक्तिशाली परानुकंपीसम (parasympathomimetic) अल्कलॉयड तथा एक उद्दीपक औषधि (ड्रग) है। यह सोलानेसी कुल के पौधों में पाया जाता है।